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Synonyms: PICD, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216
Anti-IDH1 Monoclonal Antibody
(9A285)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
| Description | Anti-IDH1 Monoclonal Antibody (9A285) is a Mouse antibody targeting IDH1. Anti-IDH1 Monoclonal Antibody (9A285) can be used in WB,IF,FCM. |
| Synonyms | PICD, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216 |
| Ig Type | IgG1 |
| Clone | 9A285 |
| Reactivity | Human,Mouse,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/50-1/250; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human IDH1 (AA: 156-298) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | IDH1 |
| Gene ID | |
| Protein Name | Isocitrate dehydrogenase [NADP] cytoplasmic |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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