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Synonyms: MOF, KAT8, hMOF
Anti-MYST1 Monoclonal Antibody
(9X554)

| Description | Anti-MYST1 Monoclonal Antibody (9X554) is a Mouse antibody targeting MYST1. Anti-MYST1 Monoclonal Antibody (9X554) can be used in WB,IHC,IF. |
| Synonyms | MOF, KAT8, hMOF |
| Ig Type | IgG2b |
| Clone | 9X554 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MYST1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KAT8 |
| Gene ID | |
| Protein Name | Histone acetyltransferase KAT8 |
| Uniprot ID |
| Molecular Weight | Theoretical: 53 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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