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Anti-FGFR4 Monoclonal Antibody (9Z569)
(Synonyms: TKF, JTK2, CD334) Copy Product Info
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Synonyms: TKF, JTK2, CD334
Catalog No. TMAT-0919 Copy Product Info
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Anti-FGFR4 Monoclonal Antibody (9Z569) is a Mouse antibody targeting FGFR4. Anti-FGFR4 Monoclonal Antibody (9Z569) can be used in IF.
Anti-FGFR4 Monoclonal Antibody
(9Z569)
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Product Introduction
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| Description | Anti-FGFR4 Monoclonal Antibody (9Z569) is a Mouse antibody targeting FGFR4. Anti-FGFR4 Monoclonal Antibody (9Z569) can be used in IF. |
| Synonyms | TKF, JTK2, CD334 |
| Ig Type | IgG1 |
| Clone | 9Z569 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line. |
| Antigen Species | Human |
| Gene Name | FGFR4 |
| Gene ID | |
| Protein Name | Fibroblast growth factor receptor 4 |
| Uniprot ID |
| Molecular Weight | Theoretical: 87.9 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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