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Anti-SLINGSHOT-1L Monoclonal Antibody (9V360)

(Synonyms: SSH1L, SSH1) Copy Product Info
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Synonyms: SSH1L, SSH1

Catalog No. TMAT-1449 Copy Product Info
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Anti-SLINGSHOT-1L Monoclonal Antibody (9V360) is a Mouse antibody targeting SLINGSHOT-1L. Anti-SLINGSHOT-1L Monoclonal Antibody (9V360) can be used in IF,FCM.

Anti-SLINGSHOT-1L Monoclonal Antibody
(9V360)

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Product Introduction

Bioactivity
Description
Anti-SLINGSHOT-1L Monoclonal Antibody (9V360) is a Mouse antibody targeting SLINGSHOT-1L. Anti-SLINGSHOT-1L Monoclonal Antibody (9V360) can be used in IF,FCM.
SynonymsSSH1L, SSH1
Ig Type
IgG1
Clone
9V360
Reactivity
Human
Application
Recommended Dose
IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.
Antigen Species
Human
Gene Name
SSH1
Gene ID
Protein Name
Protein phosphatase Slingshot homolog 1
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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