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Anti-GATA4 Monoclonal Antibody (9H331)
(Synonyms: MGC126629) Copy Product Info
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Synonyms: MGC126629
Catalog No. TMAT-1053 Copy Product Info
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Anti-GATA4 Monoclonal Antibody (9H331) is a Mouse antibody targeting GATA4. Anti-GATA4 Monoclonal Antibody (9H331) can be used in WB.
Anti-GATA4 Monoclonal Antibody
(9H331)
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Related Conjugates and Formulations
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| Description | Anti-GATA4 Monoclonal Antibody (9H331) is a Mouse antibody targeting GATA4. Anti-GATA4 Monoclonal Antibody (9H331) can be used in WB. |
| Synonyms | MGC126629 |
| Ig Type | IgG2b |
| Clone | 9H331 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors. Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. These factors recognize the GATA motif which is present in the promoters of many genes. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GATA4 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GATA4 |
| Gene ID | |
| Protein Name | Transcription factor GATA-4 |
| Uniprot ID |
| Molecular Weight | Theoretical: 46 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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