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Anti-Oncostatin M/OSM Antibody (9V884)
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Catalog No. TMAY-00849
Alias oncostatin M, OncoM
Anti-Oncostatin M/OSM Antibody (9V884) is a Rabbit antibody targeting Oncostatin M/OSM. Anti-Oncostatin M/OSM Antibody (9V884) can be used in ELISA,ICC/IF.
Anti-Oncostatin M/OSM Antibody (9V884)
Anti-Oncostatin M/OSM Antibody (9V884)
😃Good
Catalog No. TMAY-00849Alias oncostatin M, OncoM
Anti-Oncostatin M/OSM Antibody (9V884) is a Rabbit antibody targeting Oncostatin M/OSM. Anti-Oncostatin M/OSM Antibody (9V884) can be used in ELISA,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Oncostatin M/OSM Antibody (9V884) is a Rabbit antibody targeting Oncostatin M/OSM. Anti-Oncostatin M/OSM Antibody (9V884) can be used in ELISA,ICC/IF. |
| Alias | oncostatin M, OncoM |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9V884 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of OSM in jurkat cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human OSM monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm . |
| Application | ELISA,ICC/IF |
| Recommended Dose | ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Oncostatin M / OSM (rh Oncostatin M / OSM; TMPY-02364; P13725; Met1-Arg221). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surface receptors typeⅠand typeⅡ both of which share the similarity of containing protein gp130 and takes part in many bio metabolism processes including liver development, hematopoiesis, inflammation, bone formation, and destruction and possibly CNS development. Oncostatin M (OSM) was previously identified by its ability to inhibit the growth of cells from melanoma and other solid tumors. It also has been reported that OSM, like LIF, IL-6, and G-CSF, can inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells. The human form of OSM is insensitive between pH2 and 11 and resistant to heating for one hour at 56 degrees but is not stable at 90 degrees. The human OSM is produced as a precursor containing 252 amino acids, whose first 25 amino acids function as a secretory signal peptide and which on removal yields the soluble 227 amino acid pro-OSM. Removal of the C-terminal most 31 amino acids produces the fully active 196 residue form. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Oncostatin M / OSM protein (TMPY-02364) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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