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Anti-ACHE Monoclonal Antibody (9N477)
(Synonyms: YT, N-ACHE, ARACHE, ACEE) Copy Product Info
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Synonyms: YT, N-ACHE, ARACHE, ACEE
Catalog No. TMAT-0014 Copy Product Info
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Anti-ACHE Monoclonal Antibody (9N477) is a Mouse antibody targeting ACHE. Anti-ACHE Monoclonal Antibody (9N477) can be used in WB,IHC,FCM.
Anti-ACHE Monoclonal Antibody
(9N477)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-ACHE Monoclonal Antibody (9N477) is a Mouse antibody targeting ACHE. Anti-ACHE Monoclonal Antibody (9N477) can be used in WB,IHC,FCM. |
| Synonyms | YT, N-ACHE, ARACHE, ACEE |
| Ig Type | IgG1 |
| Clone | 9N477 |
| Reactivity | Human, Mouse, Monkey, Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. AChE activity may constitute a sensitive biomarker of RBC ageing in vivo, and thus, may be of aid in understanding the effects of transfusion. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ACHE expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ACHE |
| Gene ID | |
| Protein Name | Acetylcholinesterase |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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