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Anti-SNCB Antibody (9E458)
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Catalog No. TMAY-03638
Anti-SNCB Antibody (9E458) is a Mouse antibody targeting SNCB. Anti-SNCB Antibody (9E458) can be used in ELISA.
Anti-SNCB Antibody (9E458)
Anti-SNCB Antibody (9E458)
😃Good
Catalog No. TMAY-03638
Anti-SNCB Antibody (9E458) is a Mouse antibody targeting SNCB. Anti-SNCB Antibody (9E458) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SNCB Antibody (9E458) is a Mouse antibody targeting SNCB. Anti-SNCB Antibody (9E458) can be used in ELISA. |
| Ig Type | Mouse IgG1 |
| Clone | 9E458 |
| Reactivity | Human |
| Specificity | Human Beta-synuclein/SNCB |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SNCB (Q16143; aa 1-134). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Evidence of an age-related increase of β-synuclein (SNCB) in several parts of the visual system including the retina has been reported. In general, the β-synuclein protein, codified by the SNCB gene, acts as a regulator of processes triggered by α-synuclein, and its function is altered by variations in the gene sequence, while γ-synuclein, codified by the SNCG gene, seems to play a major role in certain tumoral processes. The human alpha- and beta-synuclein genes (SNCA and SNCB) are key factors for the development of Lewy body diseases. Increased β-synuclein (Sncb) expression has been described in the aging visual system. Sncb functions as the physiological antagonist of α-synuclein (Snca), which is involved in the development of neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SNCB Protein |
| Antigen Species | Human |
| Color | Transparent |
| Appearance | Liquid |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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