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Anti-NPM1 Monoclonal Antibody (9M872)
(Synonyms: NPM, B23) Copy Product Info
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Synonyms: NPM, B23
Catalog No. TMAT-0723 Copy Product Info
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Anti-NPM1 Monoclonal Antibody (9M872) is a Mouse antibody targeting NPM1. Anti-NPM1 Monoclonal Antibody (9M872) can be used in WB,IHC,IF.
Anti-NPM1 Monoclonal Antibody
(9M872)
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Related Conjugates and Formulations
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| Description | Anti-NPM1 Monoclonal Antibody (9M872) is a Mouse antibody targeting NPM1. Anti-NPM1 Monoclonal Antibody (9M872) can be used in WB,IHC,IF. |
| Synonyms | NPM, B23 |
| Ig Type | IgG1 |
| Clone | 9M872 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Nucleophosmin (NPM), also named B23 or NO38, is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. NPM has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NPM (2-265) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NPM1 |
| Gene ID | |
| Protein Name | Nucleophosmin |
| Uniprot ID |
| Molecular Weight | Theoretical: 33 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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