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Anti-MTA1 Monoclonal Antibody (9K608)
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Catalog No. TMAT-1271 Copy Product Info
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Anti-MTA1 Monoclonal Antibody (9K608) is a Mouse antibody targeting MTA1. Anti-MTA1 Monoclonal Antibody (9K608) can be used in WB,FCM.
Anti-MTA1 Monoclonal Antibody
(9K608)
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| Description | Anti-MTA1 Monoclonal Antibody (9K608) is a Mouse antibody targeting MTA1. Anti-MTA1 Monoclonal Antibody (9K608) can be used in WB,FCM. |
| Ig Type | IgG2b |
| Clone | 9K608 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MTA1 (AA: 541-715) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MTA1 |
| Gene ID | |
| Protein Name | Metastasis-associated protein MTA1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 80.8 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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