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Anti-NOTCH2 Monoclonal Antibody (9T763)

(Synonyms: hN2, HJCYS, AGS2) Copy Product Info
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Synonyms: hN2, HJCYS, AGS2

Catalog No. TMAT-1217 Copy Product Info
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Anti-NOTCH2 Monoclonal Antibody (9T763) is a Mouse antibody targeting NOTCH2. Anti-NOTCH2 Monoclonal Antibody (9T763) can be used in IHC,IF,FCM.

Anti-NOTCH2 Monoclonal Antibody
(9T763)

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Product Introduction

Bioactivity
Description
Anti-NOTCH2 Monoclonal Antibody (9T763) is a Mouse antibody targeting NOTCH2. Anti-NOTCH2 Monoclonal Antibody (9T763) can be used in IHC,IF,FCM.
SynonymshN2, HJCYS, AGS2
Ig Type
IgG2a
Clone
9T763
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human NOTCH2 (AA: extra 1391-1677) expressed in E. Coli.
Antigen Species
Human
Gene Name
NOTCH2
Gene ID
Protein Name
Neurogenic locus notch homolog protein 2
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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