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Anti-Avelumab Antibody (9X18) (Synonyms: Bavencio)

Catalog No. TMAS-00013 Copy Product Info
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Anti-Avelumab Antibody (9X18) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (9X18) can be used in ELISA, Competitive ELISA.

Anti-Avelumab Antibody (9X18)

Copy Product Info
🥰Excellent
Catalog No. TMAS-00013
Synonyms Bavencio

Anti-Avelumab Antibody (9X18) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (9X18) can be used in ELISA, Competitive ELISA.

Anti-Avelumab Antibody
(9X18)
Pack SizePriceUSA StockGlobal StockQuantity
40 μg$3057-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Avelumab Antibody (9X18) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (9X18) can be used in ELISA, Competitive ELISA.
SynonymsBavencio
Ig Type
IgG1,κ
Clone
9X18
Specificity
Avelumab
Application
Recommended Dose
ELISA: 0.001-0.1 µg/ml; Competitive ELISA: 10-50 µg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
PurificationProtein A affinity column
AppearanceLyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
FormulationLyophilized with PBS, pH 7.2, containing 0.02% sodium azide.
Research BackgroundAvelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as "immune checkpoint inhibition."
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Avelumab
Chemical Properties
Stability & Storage
Stability & StorageThe lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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