Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-ARSA Antibody (9A5)

😃Good
Catalog No. TMAY-00845
Alias TISP73, AW212749, AS-A, ASA, As-2, As2, arylsulfatase A

Anti-ARSA Antibody (9A5) is a Rabbit antibody targeting ARSA. Anti-ARSA Antibody (9A5) can be used in ELISA.

Anti-ARSA Antibody (9A5)

Anti-ARSA Antibody (9A5)

😃Good
Catalog No. TMAY-00845Alias TISP73, AW212749, AS-A, ASA, As-2, As2, arylsulfatase A
Anti-ARSA Antibody (9A5) is a Rabbit antibody targeting ARSA. Anti-ARSA Antibody (9A5) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$270 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-ARSA Antibody (9A5) is a Rabbit antibody targeting ARSA. Anti-ARSA Antibody (9A5) can be used in ELISA.
AliasTISP73, AW212749, AS-A, ASA, As-2, As2, arylsulfatase A
Ig Type
Monoclonal Rabbit IgG
Clone
9A5
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Arylsulfatase A / ARSA (rh Arylsulfatase A / ARSA; TMPY-00669; P15289-1; Met 1-Ala 507).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundArylsulfatase A (ARSA) is synthesized as a 52KDa lysosomal enzyme. It is a member of the sulfatase family that is required for the lysosomal degradation of cerebroside-3-sulfate, a sphingolipid sulfate ester and a major constituent of the myelin sheet. Arylsulfatase A is activated by a required co- or posttranslational modification with the oxidation of cysteine to formylglycine. Metachromatic leukodystrophy (MLD) is a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms caused by the deficiency of Arylsulfatase A. Deficiency of this enzyme is also found in apparently healthy individuals, a condition for which the term pseudodeficiency is introduced. ARSA forms dimers after receiving three N-linked oligosaccharides in the endoplasmic reticulum, and then the dimers are transported to the Golgi where they receive mannose 6-phosphate recognition markers. And thus, ARSA is transported and delivered to dense lysosomes in a mannose 6-phosphate receptor-dependent manner. It has been shown that within the lysosomes, the ARSA dimers can oligomerize to an octamer in a pH-dependent manner. The ARSA deficiency leads to metachromatic leucodystrophy (MLD), a lysosomal storage disorder associated with severe and progressive demyelination in he central and peripheral nervous system. Additionally, the serum level of arylsulfatase A might be helpful in diagnosis of lung and central nervous system cancer.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Arylsulfatase A / ARSA protein (TMPY-00669)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-ARSA Antibody (9A5) | purchase Anti-ARSA Antibody (9A5) | Anti-ARSA Antibody (9A5) cost | order Anti-ARSA Antibody (9A5)