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Synonyms: fibrinogen beta chain
Anti-FGB Monoclonal Antibody
(9A548)

| Description | Anti-FGB Monoclonal Antibody (9A548) is a Mouse antibody targeting FGB. Anti-FGB Monoclonal Antibody (9A548) can be used in WB. |
| Synonyms | fibrinogen beta chain |
| Ig Type | IgG1 |
| Clone | 9A548 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FGB |
| Gene ID | |
| Protein Name | Fibrinogen beta chain |
| Uniprot ID |
| Molecular Weight | Theoretical: 52 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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