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Anti-CXCL9 Antibody (6Z402)
😃Good
Catalog No. TMAY-03147
Alias chemokine (C-X-C motif) ligand 9
Anti-CXCL9 Antibody (6Z402) is a Rabbit antibody targeting CXCL9. Anti-CXCL9 Antibody (6Z402) can be used in ELISA.
Anti-CXCL9 Antibody (6Z402)
Anti-CXCL9 Antibody (6Z402)
😃Good
Catalog No. TMAY-03147Alias chemokine (C-X-C motif) ligand 9
Anti-CXCL9 Antibody (6Z402) is a Rabbit antibody targeting CXCL9. Anti-CXCL9 Antibody (6Z402) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CXCL9 Antibody (6Z402) is a Rabbit antibody targeting CXCL9. Anti-CXCL9 Antibody (6Z402) can be used in ELISA. |
| Alias | chemokine (C-X-C motif) ligand 9 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6Z402 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CXCL9 / MIG (rM CXCL9 / MIG; TMPY-02203; P18340; Thr22-Thr126). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defined; however, it is thought to be involved in T cell trafficking. CXCL9/MIG functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. CXCL9/MIG, together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. Experiment data represent novel mechanisms by which tumour cells in melanoma metastases might use the chemokine-expressing endothelium to leave the tumour and eventually to form additional metastases at distinct sites. Experiment results also improved that CXCL9/MIG plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9/MIG, and recipient CD4 lymphocytes are necessary for sustained CXCL9/MIG production and CAV development in this model. Neutralization of the chemokine CXCL9/MIG may have therapeutic potential for the treatment of chronic rejection after heart transplantation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse CXCL9 / MIG protein (TMPY-02203) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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