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ODN 1018

Name: ODN 1018
Brand: TargetMol
SKU: T74902
Rating: 4.5 (1 reviews)

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Catalog No. T74902Cas No. 937402-51-2

Alias ODN1018, 1018ISS, 1018 ISS

ODN 1018 (1018 ISS) is a synthetic oligodeoxynucleotide that functions as a Toll-like receptor 9 (TLR-9) agonist and immunostimulatory sequence, with the defined sequence 5′-TGACTGTGAACGTTCGAGATGA-3′, ODN 1018 is widely applied as a vaccine adjuvant and immunology research tool to activate innate immune responses and enhance antigen-specific immunity.

ODN 1018

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Catalog No. T74902Alias ODN1018, 1018ISS, 1018 ISSCas No. 937402-51-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$192	2-4 weeks	2-4 weeks
5 mg	$471	2-4 weeks	2-4 weeks
10 mg	$734	2-4 weeks	2-4 weeks
50 mg	Inquiry	2-4 weeks	2-4 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	ODN 1018 (1018 ISS) is a synthetic oligodeoxynucleotide that functions as a Toll-like receptor 9 (TLR-9) agonist and immunostimulatory sequence, with the defined sequence 5′-TGACTGTGAACGTTCGAGATGA-3′, ODN 1018 is widely applied as a vaccine adjuvant and immunology research tool to activate innate immune responses and enhance antigen-specific immunity.
Synonyms	ODN1018, 1018ISS, 1018 ISS

Chemical Properties

Molecular Weight	8272.3
Cas No.	937402-51-2
Sequence	DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A)

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (9.67 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.1209 mL	0.6044 mL	1.2089 mL	6.0443 mL
5 mM	0.0242 mL	0.1209 mL	0.2418 mL	1.2089 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc