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Anti-HLA-DRA Monoclonal Antibody (9B138)
(Synonyms: MLRW, HLA-DRA1) Copy Product Info
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Synonyms: MLRW, HLA-DRA1
Catalog No. TMAT-0648 Copy Product Info
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Anti-HLA-DRA Monoclonal Antibody (9B138) is a Mouse antibody targeting HLA-DRA. Anti-HLA-DRA Monoclonal Antibody (9B138) can be used in WB,IF,FCM.
Anti-HLA-DRA Monoclonal Antibody
(9B138)
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| Description | Anti-HLA-DRA Monoclonal Antibody (9B138) is a Mouse antibody targeting HLA-DRA. Anti-HLA-DRA Monoclonal Antibody (9B138) can be used in WB,IF,FCM. |
| Synonyms | MLRW, HLA-DRA1 |
| Ig Type | IgG2b |
| Clone | 9B138 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/100-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HLA-DRA |
| Gene ID | |
| Protein Name | HLA class II histocompatibility antigen, DR alpha chain |
| Uniprot ID |
| Molecular Weight | Theoretical: 28.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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