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Synonyms: CTCF
Anti-CTCF Monoclonal Antibody
(9L342)

| Description | Anti-CTCF Monoclonal Antibody (9L342) is a Mouse antibody targeting CTCF. Anti-CTCF Monoclonal Antibody (9L342) can be used in WB. |
| Synonyms | CTCF |
| Ig Type | IgG1 |
| Clone | 9L342 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.Tissue specificity: Ubiquitous. Absent in primary spermatocytes. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CTCF expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CTCF |
| Gene ID | |
| Protein Name | Transcriptional repressor CTCF |
| Uniprot ID |
| Molecular Weight | Theoretical: 83 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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