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Anti-CD84 Antibody (9Z499) (Synonyms: CD84 molecule)

Catalog No. TMAY-00255 Copy Product Info
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Anti-CD84 Antibody (9Z499) is a Rabbit antibody targeting CD84. Anti-CD84 Antibody (9Z499) can be used in ELISA,IP,WB.

Anti-CD84 Antibody (9Z499)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00255
Synonyms CD84 molecule

Anti-CD84 Antibody (9Z499) is a Rabbit antibody targeting CD84. Anti-CD84 Antibody (9Z499) can be used in ELISA,IP,WB.

Anti-CD84 Antibody
(9Z499)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD84 Antibody (9Z499) is a Rabbit antibody targeting CD84. Anti-CD84 Antibody (9Z499) can be used in ELISA,IP,WB.
SynonymsCD84 molecule
Ig Type
Rabbit IgG
Clone
9Z499
Reactivity
Human
Specificity
Human CD84
Verified Activity
1. CD84 was immunoprecipitated using:
-Lane A:0.5 mg Raw264.7 Whole Cell Lysate
-0.5 µL anti-CD84 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose.
-Primary antibody:
-Anti-CD84 rabbit monoclonal antibody, at 1:500 dilution.
-Secondary antibody:
-Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution.
-Developed using the odyssey technique.
-Performed under reducing conditions.
-Predicted band size: 62 kDa.
-Observed band size: 62 kDa.
2. Anti-CD84 rabbit monoclonal antibody at 1:500 dilution.
-Lane A: RAW264.7 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:39 kDa.
-Observed band size:39 kDa
Application
Recommended Dose
WB: 1:500-1:1000; ELISA: 1:25000-1:50000; IP: 0.2-1 μL/mg of lysate
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD84 extracellular domain (rh CD84; TMPY-00715; Met 1-Gly 225; NP_003865.1).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CD84 protein (TMPY-00715)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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