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Anti-DDR2 Monoclonal Antibody (9S773)
(Synonyms: TYRO10, TKT, NTRKR3, MIG20a) Copy Product Info
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Synonyms: TYRO10, TKT, NTRKR3, MIG20a
Catalog No. TMAT-1368 Copy Product Info
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Anti-DDR2 Monoclonal Antibody (9S773) is a Mouse antibody targeting DDR2. Anti-DDR2 Monoclonal Antibody (9S773) can be used in IHC,IF,FCM.
Anti-DDR2 Monoclonal Antibody
(9S773)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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| Description | Anti-DDR2 Monoclonal Antibody (9S773) is a Mouse antibody targeting DDR2. Anti-DDR2 Monoclonal Antibody (9S773) can be used in IHC,IF,FCM. |
| Synonyms | TYRO10, TKT, NTRKR3, MIG20a |
| Ig Type | IgG2a |
| Clone | 9S773 |
| Reactivity | Human,Mouse,Rat,Rabbit |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/ threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DDR2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DDR2 |
| Gene ID | |
| Protein Name | Discoidin domain-containing receptor 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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