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Anti-TNFSF9 Monoclonal Antibody (9J513)
(Synonyms: TNLG5A, CD137L, 4-1BB-L) Copy Product Info
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Synonyms: TNLG5A, CD137L, 4-1BB-L
Catalog No. TMAT-1022 Copy Product Info
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Anti-TNFSF9 Monoclonal Antibody (9J513) is a Mouse antibody targeting TNFSF9. Anti-TNFSF9 Monoclonal Antibody (9J513) can be used in IHC,IF,FCM.
Anti-TNFSF9 Monoclonal Antibody
(9J513)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-TNFSF9 Monoclonal Antibody (9J513) is a Mouse antibody targeting TNFSF9. Anti-TNFSF9 Monoclonal Antibody (9J513) can be used in IHC,IF,FCM. |
| Synonyms | TNLG5A, CD137L, 4-1BB-L |
| Ig Type | IgG2b |
| Clone | 9J513 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TNFSF9 (AA: Extra(50-254)) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TNFSF9 |
| Gene ID | |
| Protein Name | Tumor necrosis factor ligand superfamily member 9 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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