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Anti-MRE11 Monoclonal Antibody (9U520)
(Synonyms: MRE11B, MRE11A, HNGS1, ATLD) Copy Product Info
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Synonyms: MRE11B, MRE11A, HNGS1, ATLD
Catalog No. TMAT-1084 Copy Product Info
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Anti-MRE11 Monoclonal Antibody (9U520) is a Mouse antibody targeting MRE11. Anti-MRE11 Monoclonal Antibody (9U520) can be used in WB,IHC,FCM.
Anti-MRE11 Monoclonal Antibody
(9U520)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MRE11 Monoclonal Antibody (9U520) is a Mouse antibody targeting MRE11. Anti-MRE11 Monoclonal Antibody (9U520) can be used in WB,IHC,FCM. |
| Synonyms | MRE11B, MRE11A, HNGS1, ATLD |
| Ig Type | IgG2b |
| Clone | 9U520 |
| Reactivity | Human,Mouse,Monkey,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MRE11 (AA: 182-582) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MRE11 |
| Gene ID | |
| Protein Name | Double-strand break repair protein MRE11 |
| Uniprot ID |
| Molecular Weight | Theoretical: 80.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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