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Anti-Pan Cytokeratin Antibody (9Q604)

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Catalog No. TMAB-09955 Copy Product Info
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Anti-Pan Cytokeratin Antibody (9Q604) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (9Q604) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Pan Cytokeratin Antibody
(9Q604)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Pan Cytokeratin Antibody (9Q604) is a Mouse antibody targeting Pan Cytokeratin. Anti-Pan Cytokeratin Antibody (9Q604) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG2b, Kappa
Clone
9Q604
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCytoplasmic.
Tissue Specificityepithelial cells
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.
Concentration1mg/ml
Research BackgroundCytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Pan Cytokeratin
Antigen Species
Human
Gene Name
KRT24
Gene ID
Protein Name
Keratin, type I cytoskeletal 24
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42-64 kDa. Actual: 60,45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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