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Anti-MAPK10 Monoclonal Antibody (9J980)
(Synonyms: PRKM10, p54bSAPK, JNK3A, JNK3) Copy Product Info
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Synonyms: PRKM10, p54bSAPK, JNK3A, JNK3
Catalog No. TMAT-1117 Copy Product Info
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Anti-MAPK10 Monoclonal Antibody (9J980) is a Mouse antibody targeting MAPK10. Anti-MAPK10 Monoclonal Antibody (9J980) can be used in WB,IF.
Anti-MAPK10 Monoclonal Antibody
(9J980)
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| Description | Anti-MAPK10 Monoclonal Antibody (9J980) is a Mouse antibody targeting MAPK10. Anti-MAPK10 Monoclonal Antibody (9J980) can be used in WB,IF. |
| Synonyms | PRKM10, p54bSAPK, JNK3A, JNK3 |
| Ig Type | IgG1 |
| Clone | 9J980 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAPK10 |
| Gene ID | |
| Protein Name | Mitogen-activated protein kinase 10 |
| Uniprot ID |
| Molecular Weight | Theoretical: 53 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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