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Anti-MCAM Monoclonal Antibody (9G117)
(Synonyms: MUC18, CD146) Copy Product Info
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Synonyms: MUC18, CD146
Catalog No. TMAT-1040 Copy Product Info
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Anti-MCAM Monoclonal Antibody (9G117) is a Mouse antibody targeting MCAM. Anti-MCAM Monoclonal Antibody (9G117) can be used in WB,IHC,FCM.
Anti-MCAM Monoclonal Antibody
(9G117)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MCAM Monoclonal Antibody (9G117) is a Mouse antibody targeting MCAM. Anti-MCAM Monoclonal Antibody (9G117) can be used in WB,IHC,FCM. |
| Synonyms | MUC18, CD146 |
| Ig Type | IgG1 |
| Clone | 9G117 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MCAM |
| Gene ID | |
| Protein Name | Cell surface glycoprotein MUC18 |
| Uniprot ID |
| Molecular Weight | Theoretical: 71.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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