bio — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10545	BIO-32546		PDE
	BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.		PDE
T21868	BIO-1211		Integrin
	BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).		Integrin
TP1457	BIO-11006 acetate salt (901117-03-1 free base)	BIO-11006 acetate salt	Others
	BIO-11006 acetate salt (901117-03-1 free base) is a polyglycosylated alanine rich C kinase substrate (MARCKS) inhibitor similar to MANS peptides.		Others
T6787	BIO-acetoxime	BIA,GSK-3 Inhibitor X	Apoptosis , GSK-3 , HSV
	BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.		Apoptosis , GSK-3 , HSV
T8330	BIO-013077-01		TGF-beta/Smad
	BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.		TGF-beta/Smad
T1917	GSK 3 Inhibitor IX	BIO,GSK 3 IX,6-BIO,6-Bromoindirubin-3'-oxime,MLS 2052,6-bromoindirubin-3-oxime	Apoptosis , GSK-3 , Tyrosine Kinases , CDK
	GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex. It inhibits (GSK-3α/β)/CDK1/CDK5 activity with IC50 values of 5 nM/320 nM/83 nM, respectively.		Apoptosis , GSK-3 , Tyrosine Kinases , CDK
T10546	bio-THZ1		CDK
	bio-THZ1 is a biotinylated version of THZ1. THZ1 is a selective and irreversibly covalent CDK7 inhibitor (IC50: 3.2 nM).		CDK
T23795	BIO-7662	BIO7662
	BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.
T78122	Bio-AMS
	Bio-AMS is a potent inhibitor of bacterial biotin protein ligase, exhibiting selective activity against Mycobacterium tuberculosis (Mtb) and disrupting fatty acid and lipid biosynthesis [1] [2].
T23794	BIO592	BIO-592,BIO 592
	BIO592 is a modulator of RORγt. BIO592 triggers inverse agonism of RORγ.
T83884	Bio-Ben	Biotin-Benzoboroxole
	Bio-ben functions as a sulfenic acid probe, utilized for labeling both free sulfenic acid and cysteine sulfenic acid within proteins and peptides.
T23793	BIO399	BIO 399
	BIO399 is an agonist of the RORγt inverse.
T73821	Bio-AMS TFA
	Bio-AMS (TFA) is a potent inhibitor of bacterial biotin protein ligase, exhibiting selective efficacy against Mycobacterium tuberculosis (Mtb) by inhibiting fatty acid and lipid biosynthesis [1].
T61890	(E/Z)-BIO-acetoxime
	(E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。
T36296	BIO5192 hydrate
	BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase...
T2167	Lutidinic acid	2,4-Pyridinedicarboxylic acid,2,4-Dicarboxypyridine,2, 4-PDCA,2,4-PDCA	Histone Methyltransferase
	lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.		Histone Methyltransferase
T38888	Azide-PEG3-Desthiobiotin	Azide-PEG3-Desthiobiotin
	Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
T14577	Biotin-DADOO	EZ-Link Amine-PEO2-Biotin,Biotinyl-3,6-dioxaoctanediamine	Others
	Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) is a biotinylation reagent that can be used to synthesize a biotin-estradiol conjugate(i.e., biotin-DADOO-estradiol) to develop a direct, broad-range enzyme immunoassay to m...		Others
T3S2156	Chrysin 7-O-beta-gentiobioside	Chrysin 7-O-β-gentiobioside	Others
	Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside), a glycosylation product of Chrysin, is from Spartium junceum.		Others
T60017	5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside		Others
	5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.		Others