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Anti-TLR2 Antibody-Biotin (3U29)
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Catalog No. TMAY-00203B
Alias toll-like receptor 2
Anti-TLR2 Antibody-Biotin (3U29) is a Biotin-conjugated Rabbit antibody targeting TLR2. Anti-TLR2 Antibody-Biotin (3U29) can be used in ELISA.
Anti-TLR2 Antibody-Biotin (3U29)
Anti-TLR2 Antibody-Biotin (3U29)
😃Good
Catalog No. TMAY-00203BAlias toll-like receptor 2
Anti-TLR2 Antibody-Biotin (3U29) is a Biotin-conjugated Rabbit antibody targeting TLR2. Anti-TLR2 Antibody-Biotin (3U29) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $409 | 7-10 days |
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Chemical Properties
| Description | Anti-TLR2 Antibody-Biotin (3U29) is a Biotin-conjugated Rabbit antibody targeting TLR2. Anti-TLR2 Antibody-Biotin (3U29) can be used in ELISA. |
| Alias | toll-like receptor 2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3U29 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TLR2 / CD282 (rh TLR2 / CD282; NP_003255.2Met1-Arg587)and then biotinylated. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathogen recognition and activation of innate immunity. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 contains 14 LRR (leucine-rich) repeats and 1 TIR domain. TLR2 gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. CD282 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. It also cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. CD282 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It may also promote apoptosis in response to lipoproteins. |
| Conjucates | Biotin |
| Others Formats | Unconjugated/APC/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human TLR2 / CD282 Protein |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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