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HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
(Synonyms: NPM1-CLAV (CLAVEEVSL), NPM1-CLAV, CLAVEEVSL) Copy Product InfoSynonyms: NPM1-CLAV (CLAVEEVSL), NPM1-CLAV, CLAVEEVSL
Catalog No. TMPK-01854 Copy Product Info
HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated is expressed in E. coli. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)&CLAVEEVSL.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $147 | 7-10 days | 7-10 days | |
| 20 µg | $228 | 7-10 days | 7-10 days | |
| 50 µg | $419 | 7-10 days | 7-10 days | |
| 100 µg | $665 | 7-10 days | 7-10 days | |
| 200 µg | $1,050 | 7-10 days | 7-10 days | |
| 500 µg | $1,960 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated is expressed in E. coli. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)&CLAVEEVSL. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His-Avi |
| Accession Number | A0A140T913(HLA-A*02:01)&P61769(B2M)&CLAVEEVSL |
| Construction | Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and CLAVEEVSL peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl (pH 8.0). |
| Synonyms | NPM1-CLAV (CLAVEEVSL), NPM1-CLAV, CLAVEEVSL |
| Research Background | The nucleophosmin (NPM1) mutant protein, a leukemia-associated antigen characterized by its leukemia-restricted expression and immunogenic potential, has emerged as a promising therapeutic target for acute myeloid leukemia (AML) immunotherapy. Among its immunogenic epitopes, the CLAVEEVSL peptide derived from the full C-terminal region of the NPM1-mutated isoform demonstrates potent immunogenicity, making it a prime candidate for T cell-based immunotherapies. |
| Molecular Weight | 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated chemical structure | HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated molecular weight
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