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Anti-Ipilimumab Antibody-Biotin (6H77)

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Catalog No. TMAS-00047B
Alias Yervoy

Anti-Ipilimumab Antibody-Biotin (6H77) is a Mouse antibody targeting Ipilimumab. Anti-Ipilimumab Antibody-Biotin (6H77) can be used in ELISA.

Anti-Ipilimumab Antibody-Biotin (6H77)

Anti-Ipilimumab Antibody-Biotin (6H77)

😃Good
Catalog No. TMAS-00047BAlias Yervoy
Anti-Ipilimumab Antibody-Biotin (6H77) is a Mouse antibody targeting Ipilimumab. Anti-Ipilimumab Antibody-Biotin (6H77) can be used in ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
40 μg$3057-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Ipilimumab Antibody-Biotin (6H77) is a Mouse antibody targeting Ipilimumab. Anti-Ipilimumab Antibody-Biotin (6H77) can be used in ELISA.
SynonymsYervoy
Ig Type
IgG1
Clone
6H77
Specificity
The product is specific for Ipilimumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody Anti-Ipilimumab Antibody (9Z335) (TMAS-00048).
Application
Recommended Dose
ELISA: 0.01-0.1 µg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
PurificationProtein A affinity column
AppearanceLyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
FormulationLyophilized with PBS, pH 7.4, containing 1% BSA and 0.02% sodium azide.
Research BackgroundIpilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells.
Related Conjugates and Formulations
Conjucates
Biotin
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Ipilimumab
Chemical Properties
Stability & Storage
Stability & StorageThe lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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