nit

NIT is an HIV-1 protease inhibitor.

Nitrocefin is an antibiotic. It being sensitive to hydrolysis by all lactamases produced by gram-positive and gram-negative bacteria.

Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.

Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively.

para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II. para-Nitroblebbistatin can be used to study the specific roles of myosin II in physiology, development, and cell biology.

Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively

Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD), inhibiting AR transcriptional activity with an IC50 value of 7.4 μM. Ralaniten exhibits anticancer activity and is used to study desmoplasia-resistant prostate cancer (CRPC).

Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.

Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate and breast cancer.

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.

NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.

6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilized for research in the fields of chemistry and life sciences.

(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that induces complete regression of MYC+ lymphomas by inhibiting RNA polymerase II-mediated transcription of anti-apoptotic and pro-survival proteins.

(R)-Enitociclib, an enantiomer of BAY-1251152, is a CDK9 inhibitor with anticancer activity.

N′-(2-Chloroethyl)-N-(4-methylcyclohexyl)-N-nitrosourea has antitumor activity and is used in the treatment of Lewis lung and colon tumors.

5-Pyrrolidin-1-ylpyridine-2-carbonitrile ,with CAS No. 160017-09-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Pyrrolidin-1-ylpyridine-2-carbonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Benzothiazole-2-acetonitrile ,with CAS No. 56278-50-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Benzothiazole-2-acetonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Piperidinobenzonitrile ,with CAS No. 72752-52-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Piperidinobenzonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Piperidin-1-yl-benzonitrile ,with CAS No. 1204-85-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Piperidin-1-yl-benzonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Piperazinobenzonitrile ,with CAS No. 68104-63-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Piperazinobenzonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Morpholin-4-ylbenzonitrile ,with CAS No. 204078-31-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Morpholin-4-ylbenzonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Amino-3-(trifluoromethoxy)benzonitrile ,with CAS No. 175278-23-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Amino-3-(trifluoromethoxy)benzonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-(Trifluoromethyl)benzoylacetonitrile ,with CAS No. 27328-86-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-(Trifluoromethyl)benzoylacetonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-(4-Methylpiperazin-1-ylmethyl)benzonitrile ,with CAS No. 125743-63-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-(4-Methylpiperazin-1-ylmethyl)benzonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.