d 3

D-3 (phosphorpeptide) is an efficient, simple, and specific agent for eliminating iPSCs.

5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.

HTT-D3 is an orally active, highly efficient Huntington splicing modulator. It induces HTT mRNA degradation, reduces HTT protein levels, and inhibits P-glycoprotein (P-gp) efflux. This compound can be used in Huntington's disease research.

Vitamin D3 (cholecalciferol) is a naturally occurring form of vitamin D; once metabolically activated, it can induce cellular differentiation and cancer cell proliferation. Vitamin D3 can be used to establish kidney stone models and is also an important research target in the fields of immunology and oncology.

Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot.

3-Hydroxy agomelatine-D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine (T10114) is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).

4-Hydroxyatomoxetine-D3 is a deuterium labeled 4-Hydroxyatomoxetine. 4-Hydroxyatomoxetine (T10145) is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine (T10145) is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.

Acetazolamide-D3 is a deuterium-labeled Acetazolamide. Acetazolamide (T0813) is a potent carbonic anhydrase inhibitor.

Apixaban 13C,D3 is a deuterium labeling of Apixaban (T1736) for isotopic tracing. Apixaban 13C,D3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies

Clomipramine-D3 is the deuterium-labeled Clomipramine. Clomipramine (T21013) is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).

Clomipramine-D3 hydrochloride is the deuterium-labeled Clomipramine hydrochloride (TMSM-0794). Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).

Doxepin-D3 hydrochloride is a deuterium-labeled, stable isotope-labeled analogue of doxepin hydrochloride, primarily used as an internal standard for quantitative analysis. Doxepin hydrochloride (T1540) is a tricyclic antidepressant (TCA) and uesd for treating depression, anxiety, and insomnia.

Doxercalciferol-D3 is the deuterated form of Doxercalciferol (T6112) and ACTS as vitamin D receptor activator (VDRA), which is a vitamin D2 analogue.

Duloxetine-D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine D3 hydrochloride ( (S)-Duloxetine D3 hydrochloride) is a deuterium-labeled Duloxetine hydrochloride (TMSM-3429).

Enzalutamide-D3 is a deuterium-labeled form of the androgen receptor antagonist Enzalutamide (T6002), retaining potent anti-androgen and antineoplastic activity with an IC50 of 36 nM in LNCaP prostate cancer cells, and is primarily used in pharmacokinetic, metabolic tracing, and drug interaction studies.

Fenpiverinium-D3 bromide is a deuterium labeled Fenpiverinium bromide.

Ibuprofen-D3 is a deuterium labeled Ibuprofen. Ibuprofen (T1394) is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

Ivabradine-D3 hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent. Ivabradine hydrochloride (TMSM-3413) is the deuterium labeled Ivabradine hydrochloride.

Linezolid-D3 is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.

Meloxicam-D3 is deuterium labeled Meloxicam. Meloxicam (T0826) is a non-steroidal antiinflammatory agent, inhibits COX activity, (Target:COX-1; IC50: 36.6 μM ; (Target:COX-2; IC50: 0.49 μM).

Methimazole-D3, a deuterium-labeled version of Methimazole, serves as an antithyroid medication for treating hyperthyroidism in both humans and animals.

Methylnaltrexone-D3 bromide is the deuterium-labeled Methylnaltrexone bromide (T21422).

Mirtazapine-D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .

Naratriptan-D3 hydrochloride, the deuterium-labeled form of Naratriptan Hydrochloride (T6602), is a selective agonist of the 5-HT1 receptor subtype.