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Anti-CD32/FcγRIIA Antibody (IV.3) is a mouse inhibitory antibody that specifically targets human CD32/FcγRIIA and effectively blocks the function of the FcγRIIA receptor. It is commonly used in research on mechanisms related to inflammation and infection, including models of arthritis and Escherichia coli infection.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $173 | - | In Stock | |
| 5 mg | $518 | - | In Stock | |
| 10 mg | Preferential | - | In Stock |
| Description | Anti-CD32/FcγRIIA Antibody (IV.3) is a mouse inhibitory antibody that specifically targets human CD32/FcγRIIA and effectively blocks the function of the FcγRIIA receptor. It is commonly used in research on mechanisms related to inflammation and infection, including models of arthritis and Escherichia coli infection. |
| In vitro | Anti-CD32/FcγRIIA Antibody (IV.3) at 10 μg/mL and incubation for 30 minutes reduces the phagocytic ability of skin-derived and in vitro-induced Langerhans cells and dermal dendritic cells against Staphylococcus aureus and Escherichia coli [1]. |
| In vivo | Anti-CD32/FcγRIIA Antibody (IV.3) F(ab′)₂ fragment administered intravenously at 1 mg/g every 2 days inhibits the progression of arthritis in transgenic hFcγRIIA mice in a collagen antibody-induced arthritis (CAIA) model [2]. |
| Clone | IV.3 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | FcgR2a/CD32a |
| Molecular Weight | 150 kDa |
| Isotype | Mouse IgG2b |
| Recommended Isotype Control |
| Storage | Store at -20°C Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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