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Anti-SLAMF6 Antibody-FITC (4Z355)
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Catalog No. TMAY-02159F
Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody-FITC (4Z355) is a FITC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-FITC (4Z355) can be used in FCM.
Anti-SLAMF6 Antibody-FITC (4Z355)
Anti-SLAMF6 Antibody-FITC (4Z355)
😃Good
Catalog No. TMAY-02159FAlias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody-FITC (4Z355) is a FITC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-FITC (4Z355) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $81 | 7-10 days | |
| 100 T | $258 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SLAMF6 Antibody-FITC (4Z355) is a FITC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-FITC (4Z355) can be used in FCM. |
| Alias | SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Z355 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human SLAMF6(CD352). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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