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Anti-CD3E Antibody (1S389)
😃Good
Catalog No. TMAB-03975
Anti-CD3E Antibody (1S389) is a Mouse antibody targeting CD3E. Anti-CD3E Antibody (1S389) can be used in IF, IHC-Fr, IHC-P, WB.
Anti-CD3E Antibody (1S389)
Anti-CD3E Antibody (1S389)
😃Good
Catalog No. TMAB-03975
Anti-CD3E Antibody (1S389) is a Mouse antibody targeting CD3E. Anti-CD3E Antibody (1S389) can be used in IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD3E Antibody (1S389) is a Mouse antibody targeting CD3E. Anti-CD3E Antibody (1S389) can be used in IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 1S389 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IF=1:200-800; IHC-Fr=1:200-800; IHC-P=1:200-800; WB=1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2. |
| Immunogen | KLH conjugated synthetic peptide: mouse CD3E |
| Antigen Species | Mouse |
| Gene Name | CD3E |
| Gene ID | |
| Protein Name | T-cell surface glycoprotein CD3 epsilon chain |
| Uniprot ID | |
| Function | The CD3 complex mediates signal transduction. |
| Molecular Weight | Theoretical: 20 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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