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Anti-human CD35 Antibody (5H190)
😃Good
Catalog No. TMAB-07405
Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM.
Anti-human CD35 Antibody (5H190)
Anti-human CD35 Antibody (5H190)
😃Good
Catalog No. TMAB-07405
Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $352 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| Clone | 5H190 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 2μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Research Background | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020] |
| Gene Name | CR1 |
| Gene ID | |
| Protein Name | Complement receptor type 1 |
| Function | Mediates cellular binding of particles and immune complexes that have activated complement. |
| Molecular Weight | Theoretical: 274 kDa. Actual: 160, 190, 220, and 250 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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