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Anti-human CD35 Antibody (5H190)
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Catalog No. TMAB-07405
Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM.
Anti-human CD35 Antibody (5H190)
Anti-human CD35 Antibody (5H190)
Copy Product Info😃Good
Catalog No. TMAB-07405
Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $352 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| Clone | 5H190 |
| Reactivity | Human |
| Verified Activity | Blank control: HEL. Primary Antibody (green line): Mouse Anti-human CD35 antibody (TMAB-07405) Dilution: 2 μg/Test; Secondary Antibody (white blue line) : Goat anti-mouse IgG-FITC Dilution: 0.5 μg/Test. Isotype control (orange line): Normal Mouse IgG Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed. |
| Application | |
| Recommended Dose | FCM: 2μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Research Background | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020] |
| Gene Name | CR1 |
| Gene ID | |
| Protein Name | Complement receptor type 1 |
| Function | Mediates cellular binding of particles and immune complexes that have activated complement. |
| Molecular Weight | Theoretical: 274 kDa. Actual: 160, 190, 220, and 250 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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