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Anti-human CD38 Antibody (2D610) is a Mouse antibody targeting human CD38. Anti-human CD38 Antibody (2D610) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $352 | 7-10 days | 7-10 days |
| Description | Anti-human CD38 Antibody (2D610) is a Mouse antibody targeting human CD38. Anti-human CD38 Antibody (2D610) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| Clone | 2D610 |
| Reactivity | Human |
| Verified Activity | Blank control (black line): Ramos. Primary Antibody (green line): Mouse Anti-human CD38 antibody (TMAB-07406) Dilution: 1 μg/Test; Secondary Antibody (white blue line): Goat anti-mouse IgG-FITC Dilution: 0.5 μg/Test. Isotype control (orange line): Normal Mouse IgG Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed. |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| Immunogen | KLH conjugated synthetic peptide: human CD38 |
| Antigen Species | Human |
| Gene Name | CD38 |
| Gene ID | |
| Protein Name | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| Uniprot ID | |
| Function | Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
| Molecular Weight | Theoretical: 34 kDa. Actual: 45 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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