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Anti-SLAMF6 Antibody (1R816) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (1R816) can be used in ELISA,ELISA(Det).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $92 | 7-10 days | 7-10 days | |
| 100 μL | $269 | 7-10 days | 7-10 days |
| Description | Anti-SLAMF6 Antibody (1R816) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (1R816) can be used in ELISA,ELISA(Det). |
| Synonyms | SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352 |
| Ig Type | Rabbit IgG |
| Clone | 1R816 |
| Reactivity | Human |
| Specificity | Human SLAMF6 No cross-reactivity in ELISA with Human SLAMF7 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human Ly108 / SLAMF6 protein (TMPY-01914) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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