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Anti-SLAMF6 Antibody (1R670)
😃Good
Catalog No. TMAY-02157
Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody (1R670) is a Mouse antibody targeting SLAMF6. Anti-SLAMF6 Antibody (1R670) can be used in ELISA.
Anti-SLAMF6 Antibody (1R670)
Anti-SLAMF6 Antibody (1R670)
😃Good
Catalog No. TMAY-02157Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody (1R670) is a Mouse antibody targeting SLAMF6. Anti-SLAMF6 Antibody (1R670) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352 |
| Ig Type | Mouse IgG1 |
| Clone | 1R670 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; TMPY-01914; Q96DU3-1; Met 1-Met 226). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Ly108 / SLAMF6 protein (TMPY-01914) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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