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Anti-SLAMF6 Antibody (4Z355) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (4Z355) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | 254 € | 7-10 days |
Description | Anti-SLAMF6 Antibody (4Z355) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (4Z355) can be used in FCM. |
Alias | SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4Z355 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with purified anti-Human SLAMF6(CD352), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | FCM: 1:25-1:100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
Conjucates | Unconjugated |
Others Formats | APC/FITC/PE |
Antibody Types Available | 4 |
Immunogen | Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914) |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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