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Anti-mouse CD3 Antibody (8I639)
😃Good
Catalog No. TMAB-08953
Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM.
Anti-mouse CD3 Antibody (8I639)
Anti-mouse CD3 Antibody (8I639)
😃Good
Catalog No. TMAB-08953
Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $354 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM. |
| Ig Type | Rat IgG2b, k |
| Clone | 8I639 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2. |
| Gene Name | CD3E |
| Gene ID | |
| Protein Name | T-cell surface glycoprotein CD3 epsilon chain |
| Function | The CD3 complex mediates signal transduction. |
| Molecular Weight | Theoretical: 20 kDa. Actual: 20 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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