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Anti-mouse CD3 Antibody (8I639)

Catalog No. TMAB-08953 Copy Product Info
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Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM.

Anti-mouse CD3 Antibody (8I639)

Copy Product Info
🥰Excellent
Catalog No. TMAB-08953

Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM.

Anti-mouse CD3 Antibody
(8I639)
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$3547-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM.
Ig Type
Rat IgG2b, k
Clone
8I639
Reactivity
Mouse
Verified Activity
scatter diagram showing mouse spleen cells stained with TMAB-08953. The cells were incubated with the antibody (TMAB-08953,1 μg/Test) for 30 min at 22°C. The secondary antibody used for 40 min at room temperature.Acquisition of >20,000 events was performed.
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesRat
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundCD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
Antigen Details
Gene Name
CD3E
Gene ID
Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Function
The CD3 complex mediates signal transduction.
Chemical Properties
Molecular WeightTheoretical: 20 kDa. Actual: 20 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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