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Anti-human CD33 Antibody (2W90)
😃Good
Catalog No. TMAB-07403
Anti-human CD33 Antibody (2W90) is a Mouse antibody targeting human CD33. Anti-human CD33 Antibody (2W90) can be used in FCM.
Anti-human CD33 Antibody (2W90)
Anti-human CD33 Antibody (2W90)
😃Good
Catalog No. TMAB-07403
Anti-human CD33 Antibody (2W90) is a Mouse antibody targeting human CD33. Anti-human CD33 Antibody (2W90) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $354 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-human CD33 Antibody (2W90) is a Mouse antibody targeting human CD33. Anti-human CD33 Antibody (2W90) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| Clone | 2W90 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Monocytic/myeloid lineage cells. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Concentration | 1mg/ml |
| Research Background | Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | KLH conjugated synthetic peptide: human CD33 |
| Antigen Species | Human |
| Gene Name | CD33 |
| Gene ID | |
| Protein Name | Myeloid cell surface antigen CD33 |
| Uniprot ID | |
| Function | Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). |
| Molecular Weight | Theoretical: 40/37 kDa. Actual: 67 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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