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Anti-CD32/FcRII-b Antibody (6K455)

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Catalog No. TMAB-03953

Anti-CD32/FcRII-b Antibody (6K455) is a Mouse antibody targeting CD32/FcRII-b. Anti-CD32/FcRII-b Antibody (6K455) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-CD32/FcRII-b Antibody (6K455)

Anti-CD32/FcRII-b Antibody (6K455)

😃Good
Catalog No. TMAB-03953
Anti-CD32/FcRII-b Antibody (6K455) is a Mouse antibody targeting CD32/FcRII-b. Anti-CD32/FcRII-b Antibody (6K455) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD32/FcRII-b Antibody (6K455) is a Mouse antibody targeting CD32/FcRII-b. Anti-CD32/FcRII-b Antibody (6K455) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
6K455
Reactivity
Human
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane; Single-pass type I membrane protein.
Tissue SpecificityIs the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Antigen Details
Immunogen
Recombinant Protein: Human Fc gamma RIIB/C (CD32b/c)
Antigen Species
Human
Gene Name
FCGR2B
Gene ID
2213
Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-b
Uniprot ID
P31994
Function
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Chemical Properties
Molecular WeightTheoretical: 34 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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