receptor antagonist

A unique collection of 2400 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;

A unique collection of 280 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes. Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases. TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

A unique collection of 924 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs;

A unique collection of 815 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;

678 hypertension-related small molecules for high-throughput and high-content screening.

A unique collection of 240 calcium channel blockers and agonists for high throughput and high content screening;

A unique collection of 89 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.