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Sulotroban

Name: Sulotroban
Brand: TargetMol
SKU: T68022
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T68022Cas No. 72131-33-0

sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.

Sulotroban

🥰Excellent

Purity: 99.98%

Catalog No. T68022Cas No. 72131-33-0

sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$54	In Stock	In Stock
5 mg	$126	In Stock	In Stock
10 mg	$186	In Stock	In Stock
25 mg	$352	In Stock	In Stock
50 mg	$473	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.98%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
In vivo	Sulotroban (5 mg/kg; i.v.; cat;) did not alter baseline vascular pressures in the cat and responses to the PG and TXA2/PGH2 precursor, arachidonic acid, were reduced. The present data show that sulotroban selectively blocks TXA2/PGH2 receptor-mediated responses in a competitive and reversible manner in the pulmonary vascular bed.[4]

Chemical Properties

Molecular Weight	335.37
Formula	C₁₆H₁₇NO₅S
Cas No.	72131-33-0
Smiles	C(CNS(=O)(=O)C1=CC=CC=C1)C2=CC=C(OCC(O)=O)C=C2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (149.09 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (7.45 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9818 mL	14.9089 mL	29.8178 mL	149.0891 mL
5 mM	0.5964 mL	2.9818 mL	5.9636 mL	29.8178 mL
10 mM	0.2982 mL	1.4909 mL	2.9818 mL	14.9089 mL
20 mM	0.1491 mL	0.7454 mL	1.4909 mL	7.4545 mL
50 mM	0.0596 mL	0.2982 mL	0.5964 mL	2.9818 mL
100 mM	0.0298 mL	0.1491 mL	0.2982 mL	1.4909 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc