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S 32212 hydrochloride

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Catalog No. T23292Cas No. 847871-78-7
Alias S32212 hydrochloride

S 32212 hydrochloride is a high-affinity inverse agonist at the 5-HT2C receptor (pKi = 8.18) and an antagonist at the α2-adrenergic receptor (Ki = 5.8 nM), potentiating norepinephrine with antidepressant and anxiolytic effects.

S 32212 hydrochloride

S 32212 hydrochloride

😃Good
Purity: 99.57%
Catalog No. T23292Alias S32212 hydrochlorideCas No. 847871-78-7
S 32212 hydrochloride is a high-affinity inverse agonist at the 5-HT2C receptor (pKi = 8.18) and an antagonist at the α2-adrenergic receptor (Ki = 5.8 nM), potentiating norepinephrine with antidepressant and anxiolytic effects.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$89-In Stock
5 mg$343-In Stock
10 mg$512-In Stock
25 mg$833-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.57%
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Product Introduction

Bioactivity
Description
S 32212 hydrochloride is a high-affinity inverse agonist at the 5-HT2C receptor (pKi = 8.18) and an antagonist at the α2-adrenergic receptor (Ki = 5.8 nM), potentiating norepinephrine with antidepressant and anxiolytic effects.
SynonymsS32212 hydrochloride
Chemical Properties
Molecular Weight452.98
FormulaC25H29ClN4O2
Cas No.847871-78-7
SmilesCl.O=C(NC1=CC=C(OC)C(=C1)N2CCN(C)CC2)N3C=4C=CC=5C=CC=CC5C4CC3
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (176.61 mM), Sonication is recommended.
DMSO: 80 mg/mL (176.61 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.2076 mL11.0380 mL22.0760 mL110.3801 mL
5 mM0.4415 mL2.2076 mL4.4152 mL22.0760 mL
10 mM0.2208 mL1.1038 mL2.2076 mL11.0380 mL
20 mM0.1104 mL0.5519 mL1.1038 mL5.5190 mL
50 mM0.0442 mL0.2208 mL0.4415 mL2.2076 mL
100 mM0.0221 mL0.1104 mL0.2208 mL1.1038 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

S-32212 HydrochlorideS 32212 Hydrochloride
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