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NNC 92-1687
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Catalog No. T28182Cas No. 22903-37-3
Alias NNC92-1687, NNC-92-1687
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
NNC 92-1687
Copy Product Info🥰Excellent
Purity: 99.96%
Catalog No. T28182Alias NNC92-1687, NNC-92-1687Cas No. 22903-37-3
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $396 | In Stock | In Stock | |
| 5 mg | $878 | In Stock | In Stock | |
| 10 mg | $1,180 | In Stock | In Stock | |
| 25 mg | $1,580 | In Stock | In Stock | |
| 50 mg | $1,980 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $579 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.96%
Appearance:Solid
Color:White
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Product Introduction
NNC 92-1687 AI Summary
NNC 92-1687 has been evaluated for its binding affinity towards the cloned human Glucagon receptor in BHK cells, showing a Ki value of 20000.0 nM. Additionally, this compound exhibits bioactivity as an inhibitor of placental alkaline phosphatase. It has demonstrated IC50 values of 4790.0 nM and 5440.0 nM in the Luminescent Assay for HTS discovery and an In Vitro TNAP Dose Response Luminescent Assay, respectively, indicating its potential as an enzyme inhibitor..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes. |
| Synonyms | NNC92-1687, NNC-92-1687 |
| Molecular Weight | 300.33 |
| Formula | C15H12N2O3S |
| Cas No. | 22903-37-3 |
| Smiles | S(CC(=O)C1=CC(O)=C(O)C=C1)C=2NC=3C(N2)=CC=CC3 |
| Relative Density. | 1.54 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (166.48 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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