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Aramisulpride (hydrochloride) is a 5-HT7 receptor antagonist with a Ki value of 22 nM. It also acts as a D2/D3 receptor antagonist, exhibiting a Ki value of 140 nM for D2 receptors and 13.9 nM for D3 receptors. This compound is utilized in the study of psychiatric disorders.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | Aramisulpride (hydrochloride) is a 5-HT7 receptor antagonist with a Ki value of 22 nM. It also acts as a D2/D3 receptor antagonist, exhibiting a Ki value of 140 nM for D2 receptors and 13.9 nM for D3 receptors. This compound is utilized in the study of psychiatric disorders. |
| Targets&IC50 | 5-HT7 receptor:22 nM (Ki) |
| Synonyms | (R)-Esamisulpride hydrochloride, (R)-DAN 2163 hydrochloride, (R)-Amisulpride hydrochloride |
| Molecular Weight | 405.94 |
| Formula | C17H28ClN3O4S |
| Cas No. | 2129505-46-8 |
| Smiles | C(NC[C@@H]1N(CC)CCC1)(=O)C2=C(OC)C=C(N)C(S(CC)(=O)=O)=C2.Cl |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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