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TCMCB07 acetate(1456699-27-6 Free base)
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Catalog No. T80540L
TCMCB07 acetate(1456699-27-6 Free base), a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia.
TCMCB07 acetate(1456699-27-6 Free base)
🥰Excellent
Catalog No. T80540L
TCMCB07 acetate(1456699-27-6 Free base), a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia.
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Product Introduction
Bioactivity
Chemical Properties
| Description | TCMCB07 acetate(1456699-27-6 Free base), a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia. |
| Molecular Weight | 1290.53 |
| Formula | C65H91N15O13 |
| Smiles | O=C([C@@H](NC([C@H](NC([C@@]1([H])N(CCC1)C([C@H](CC(NCCCC[C@H](NC2=O)C(N[C@H](C(C)C)C(N3[C@H](CCC3)C(N)=O)=O)=O)=O)NC([C@@H](NC(C)=O)CCCC)=O)=O)=O)CC4=CC5=C(C=CC=C5)C=C4)=O)CCCNC(N)=N)N[C@H]2CC6=CNC7=CC=CC=C67.CC(O)=O |
| Relative Density. | no data available |
| Sequence | Ac-Nle-Asp(1)-Pro-D-2Nal-Arg-Trp-Lys(1)-DL-Val-D-Pro-NH2 |
| Sequence Short | XDPXRWKVP |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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