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(R)-CJ 11974

Name: (R)-CJ 11974
Brand: TargetMol
SKU: T68068L
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T68068LCas No. 187281-35-2

(R)-CJ 11974: non-peptide NK1 receptor antagonist, may relieve pain and prevent chemo-induced vomiting.

(R)-CJ 11974

🥰Excellent

Purity: 97.15%

Catalog No. T68068LCas No. 187281-35-2

(R)-CJ 11974: non-peptide NK1 receptor antagonist, may relieve pain and prevent chemo-induced vomiting.

Pack Size	Price	Availability
1 mg	$82	In Stock
5 mg	$181	In Stock
10 mg	$267	In Stock
25 mg	$413	In Stock
50 mg	$592	In Stock
100 mg	$819	In Stock
200 mg	$1,090	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:97.15%

ee:98.1%

Resource Download

COA HPLC CSFC HNMR

Product Introduction

Bioactivity

Description

(R)-CJ 11974: non-peptide NK1 receptor antagonist, may relieve pain and prevent chemo-induced vomiting.

Chemical Properties

Molecular Weight	454.65
Formula	C₃₁H₃₈N₂O
Cas No.	187281-35-2
Smiles	[C@@H]([C@@H]1[C@H](NCC2=C(OC)C=CC(C(C)C)=C2)C3CCN1CC3)(C4=CC=CC=C4)C5=CC=CC=C5
Relative Density.	no data available
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (120.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1995 mL	10.9975 mL	21.9949 mL	109.9747 mL
5 mM	0.4399 mL	2.1995 mL	4.3990 mL	21.9949 mL
10 mM	0.2199 mL	1.0997 mL	2.1995 mL	10.9975 mL
20 mM	0.1100 mL	0.5499 mL	1.0997 mL	5.4987 mL
50 mM	0.0440 mL	0.2199 mL	0.4399 mL	2.1995 mL
100 mM	0.0220 mL	0.1100 mL	0.2199 mL	1.0997 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc