Losartan D4

Name: Losartan D4
Brand: TargetMol
SKU: T11870
Price: 172 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11870Cas No. 1030937-27-9

Alias Losartan-d4, DuP-753-d4, DuP-753 D4

Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).

Losartan D4

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Catalog No. T11870Alias Losartan-d4, DuP-753-d4, DuP-753 D4Cas No. 1030937-27-9

Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).

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1 mg	$172	-	In Stock

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Product Introduction

Bioactivity

Description	Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).
In vitro	Losartan D4 can serve as a tracer and also as an internal standard in NMR, GC-MS, or LC-MS analysis for quantitative purposes.
Synonyms	Losartan-d4, DuP-753-d4, DuP-753 D4

Chemical Properties

Molecular Weight	426.94
Formula	C₂₂H₂₃ClN₆O
Cas No.	1030937-27-9
Smiles	C(N1C(CCCC)=NC(Cl)=C1CO)C2=C(C(=C(C(=C2[2H])[2H])C3=C(C=CC=C3)C=4NN=NN4)[2H])[2H]
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	Ethanol: ≥ 32 mg/mL, Sonication is recommended. DMSO: ≥ 32 mg/mL, Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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